冠心病患者血清超敏C-反应蛋白测定的临床意义

目的探讨超敏C-反应蛋白（hs-CRP）与冠心病严重程度的关系。方法138例冠心病患者中，稳定型心绞痛（SAP组）46例、不稳定型心绞痛（UAP组）52例、急性心肌梗死（AMI组）40例和健康体检者（对照组）60例的血清hs-CRP和肌酸激酶（CK）、肌酸激酶同工酶（CK—MB）含量进行测定比较。结果冠心病组血清hs—CRP水平显著高于对照组，其中AMI组hs—CRP水平显著高于SAP和UAP组，UAP组高于SAP组。AMI组CK、CK—MB水平显著高于UAP、SAP和对照组，差异有统计学意义（P〈0．05）。结论hs-CRP水平高低可反映冠心病患者病变的程度。

Clinical study on the significance of serum high-sensitivity C-reactive protein in patients with coronary heart disease

Objective To investigate the relationship between high-sensitivity C-reactive protein（hs-CRP）and the serum level of coronary heart disease（CHD）. Methods 138 cases patients with CHD were divided into stable angina pectoris （ SAP group,46 cases）, unstable angina pectoris （ UAP group, 52 cases） and acute myocardial infarction （ AMI group, 40 cases）. There were 60 cases healthy people in control group. All of the samples were determined the serum hs-CRP, CK and CK- MB concentrations. Results The serum hs-CRP level in patients with CHD was significantly higher than that in normal control group. The serum hs-CRP level of AMI group was significantly higher than that in SAP group and UAP group, and UAP group was significantly higher than SAP group. Among all four groups, the serum levels of CK and CK-MB were the highest, the differences were statistically significant（P 〈 0. 05 ）. Conclusion The level of hs-CRP can closely associate with the severity of CHD.