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Modulation of the immune response to HBV vaccination by hemodialysis membranes |
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| Authors: | Dede Fatih Yıldız Ayla Aylı Deniz Çolak Nujen Odabaş Ali Rıza Akoğlu Hadim Eskioğlu Erdal Covic Adrian |
| Affiliation: | (1) Department of Nephrology, Ankara Numune Training and Research Hospital, Samanpazari/Ankara, 06530, Turkey;(2) Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey;(3) Department of Nephrology Clinic and Dialysis and Transplantation Center, ‘‘C. I. PARHON’’ University Hospital, Lasi, Romania |
| Abstract: | IntroductionSeroconversion response to Hepatitis B virus (HBV) vaccination is limited in uremic patients because of impaired humoral and cellular immune activity. Recent studies show that high-flux (HF) hemodialysis (HD) membranes can improve T cell functions and decrease the proinflammatory cytokine activation more effectively than low-flux (LF) membranes. In regard to HF membranes may have immune modulator effects; we compared the antibody responses to hepatitis B vaccination between HF HD and LF HD membranes. |
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