| 垂体泌乳素腺瘤的伽玛刀治疗 |
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| 引用本文： | 马志明,仇斌,侯永宏,刘运生. 垂体泌乳素腺瘤的伽玛刀治疗[J]. 中南大学学报(医学版), 2006, 31(5): 714-716 |
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| 作者姓名： | 马志明 仇斌 侯永宏 刘运生 |
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| 作者单位： | 中南大学湘雅医院神经外科,长沙,410008;中南大学湘雅医院神经外科,长沙,410008;中南大学湘雅医院神经外科,长沙,410008;中南大学湘雅医院神经外科,长沙,410008 |
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| 摘 要： | 目的：研究伽玛刀治疗垂体泌乳素瘤的效果。方法：伽玛刀治疗垂体泌乳素瘤89例，随访51例，肿瘤周边放射剂量18～35（平均26.1）Gy，中心剂量36～60（平均50．41）Gy，肿瘤直径5～26（平均15.5）mm。结果：随访6～108（平均37）月。肿瘤的生长控制率为100％，内分泌缓解率40．0％，垂体功能低下发生率17.6％。结论：对尚未压迫视路的泌乳素瘤（尤其是微腺瘤），伽玛刀可作为初始治疗方法。
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| 关 键 词： | 垂体腺瘤 泌乳素瘤 伽玛刀 |
| 文章编号： | 1672-7347（2006）05-0720-03 |
| 收稿时间： | 2006-08-12 |
| 修稿时间： | 2006-08-12 |
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| MA Zhi-ming,QIU Bin,HOU Yong-hong,LIU Yun-sheng.
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| Authors: | MA Zhi-ming QIU Bin HOU Yong-hong LIU Yun-sheng |
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| Affiliation: | Department of Neurological Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. mazhiming64@yahoo.com.cn |
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| Abstract: | OBJECTIVE: To evaluate the outcome of gamma knife for prolactinomas. METHODS: Eighty-nine patients were treated by gamma knife and 51 were followed up. The dose to the tumor margin ranged from 18 Gy to 35 Gy (mean 26.1 Gy). The maximum radiation dose varied from 36 Gy to 60 Gy (mean 50.41 Gy). The mean tumor diameter was 15.5 mm (5 - 26 mm). RESULTS: The follow-up data were available for 51 patients ranging from 6 to 108 months (mean 37 months). The tumor growth control rate was 100%. The endocrinological remission rate was 40%. The rate of hypopituitarism was 17.6%. CONCLUSION: Gamma knife radiosurgery can be used as a primary treatment for selected prolactinomas,especially for pituitary microadenomas. |
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| Keywords: | pituitary adenoma prolactinoma gamma knife |
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