浙江省温州市瓯海区居民血脂异常流行特点及相关因素分析

目的 了解浙江省温州市瓯海区居民血脂异常流行特点及相关因素,为进一步制定血脂异常预防控制策略提供依据。方法 采用多阶段整群随机抽样的方法,对3905名18岁以上常住居民,进行问卷调查、体格检查和实验室检测。结果 调查人群血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)均值(mmol/L)分别为5.27、1.60、1.37和3.19,异常率分别为18.7%、17.1%、14.1%和15.3%。总血脂异常率为39.7%,标化异常率为36.0%;血脂边缘异常率为28.0%,标化边缘异常率为27.2%。血脂异常率男性高于女性,并随年龄的增长而升高。对血脂异常各组份分析,TC和LDL-C均随年龄的增加而升高,TG、HDL-C与年龄组间无差异,HDL-C异常率男性高于女性,LDL-C异常率女性高于男性。血脂异常知晓率为8.1%,年龄组和性别之间无差异。Logistic多因素回归分析,高尿酸血症、中心性肥胖、糖尿病、高血压是血脂异常患病的相关因素或聚集疾病。结论 温州市瓯海区居民血脂异常患病率较高,而血脂异常知晓率较低,应引起重视,积极采取相应干预措施。

Prevalence of dyslipidemia and related factors in Ouhai district of Wenzhou,Zhejiang

Objective To understand the prevalence of dyslipidemia and related factors in residents of Wenzhou and provide evidence for the development of the prevention and control measure. Methods With multistage random cluster sampling, 3 905 local residents aged 18 years were randomly selected in Ouhai district of Wenzhou for a cross-sectional study, including questionnaire survey, physical examination and laboratory test. Results The average levels of TC, TG, HDL-C and LDL-C (mmol/L) were 5.27, 1.60, 1.37 and 3.19, respectively. The abnormal rates were 18.7%, 17.1%, 14.1% and 15.3%, respectively. The overall prevalence of dyslipidemia was 39.7% and the standardized prevalence of dyslipidemia was 36.0%. The prevalence of borderline dyslipidemia was 28.0% and the standardized prevalence of borderline dyslipidemia was 27.2%. The dyslipidemia rate was higher in males than in females, and increased with age. TC and LDL-C levels increased with the age, the differences in TG and HDL-C levels had no significance among different age groups, the abnormal rate of HDL-C level was higher in males than in females. The abnormal rate of LDL-C level was higher in females than in males. The awareness rate of dyslipidemia related knowledge was 8.1%, the age and gender specific differences had no significance. Logistic regression analysis showed that hyperuricemia, central obesity, diabetes and hypertension were the risk factors for dyslipidemia or related diseases. Conclusion The prevalence of dyslipidemia was high in the residents in Ouhai, but their awareness of dyslipidemia was low. It is necessary to take targeted comprehensive prevention and intervention measures according to the characteristics of dyslipidemia prevalence.