广州市2010-2014年恙虫病流行特征及时空聚集性分析

目的 了解广州市2010-2014年间恙虫病流行特征，探讨其时空聚集性。方法 收集2010-2014年广州市恙虫病资料，描述其三间分布特征，采用时空扫描统计量分析其时空聚集性。结果 2010-2014年广州市恙虫病的总发病例数3 838例，平均发病率6.25/10万，男女发病率分别为5.62/10万和6.46/10万。60～69岁发病率最高（24.69/10万）。2012年从化市和2013年南沙区发病率分别为31.05/10万和34.57/10万。2014年前的聚类区主要集中于从化市、番禺区和南沙区等地，而2014年越秀和天河同样发展成为新聚类区。结论 广州市恙虫病发病风险高，亟待采取有效的预防控制措施。

The epidemic characteristic and spatial-temporal clusters of scrub typhus in Guangzhou City, 2010-2014

Objective To explore the epidemic characteristics and spatial-temporal clusters of scrub typhus in Guangzhou. Methods The information about scrub typhus cases from 2010 to 2014 in Guangzhou was collected. The distributions of scrub typhus cases of time, space and population were described. Space-time scan statistics were used to explore clusters. Results Totally 3 838 scrub typhus cases were reported between 2010 and 2014, and the average incidence rate was 6.25 cases per 100 000 people. The incidence rates of males and females were 5.62 cases per 100 000 people and 6.46 cases per 100 000 people respectively. The 60-69 age group showed the highest incidence rate (24.69 cases per 100 000 people). Conghua and Nansha districts (31.05 cases per 100 000 people vs 34.57 cases per 100 000 people) demonstrated higher incidence rate than other districts. The clusters were located on suburbs or rural areas such as Conghua, Panyu and Nansha before 2014, but Yuexiu and Tianhe were newly developed into clusters in 2014. Conclusions The risk of scrub typhus is high in Guangzhou, and effective prevention and control measures should be implemented timely.