广州市2004-2013年户籍人口宫颈癌与宫体癌死亡趋势分析与比较

目的 分析与比较广州市2004-2013年户籍人口宫颈癌和宫体癌的死亡情况及变化趋势，为两种癌症的防治策略提供数据支持。方法 收集2004-2013年广州市两种癌症全市发病和中心城市6区的死亡及户籍人口资料，计算粗发病和死亡率及世界人口标化率（世标率）。利用Jointpoint Regression Program软件统计时间变化趋势。结果 2004-2013年广州市宫颈癌和宫体癌的年平均发病世标率分别为9.76/10万和8.54/10万；死亡世标率分别为 1.76/10万和0.95/10万；发病年龄中位数分别为47岁和52岁。死亡率宫颈癌从30~岁组逐渐上升，宫体癌从40~岁组持续上升；10年来宫颈癌和宫体癌发病均呈上升趋势，年度变化百分比（average annual percent change，APC）分别为2.97%（Z=3.134，95%CI:0.8%~5.2%）和2.03%（Z=1.804，95%CI:-0.6%~4.8%）；同期宫颈癌和宫体癌死亡也呈上升趋势，APC分别为3.35%（Z=1.323，95%CI:-2.4%~9.4%）和14.33%（Z=4.626，95%CI:6.9%~22.2%），增长幅度分别为29.49%和216.28%。结论 广州市近10年来，虽然宫颈癌死亡率高于宫体癌，但宫体癌的死亡率上升迅速，增长速度明显高于宫颈癌。故在开展宫颈癌筛查项目的同时，重视宫体癌的防治，加强宫体癌预防措施的宣教。

Analysis on cervical cancer and corpus uteri cancer mortality in local population in Guangzhou,2004-2013

Objective To investigate the mortality trends of cervical cancer and corpus uteri cancer in local population in Guangzhou from 2004 to 2013, and provide evidence for the prevention and control of cervical cancer and corpus uteri cancer. Methods The incidence and mortality data of cervical cancer and corpus uteri cancer as well as local population data in Guangzhou from 2004-2013 were collected, the crude incidence/mortality rates, aged standardized incidence rate (AISR) and age standardized mortality rate (ASMR) based on world population were calculated and the incidence and mortality trends were analyzed with Join-point regression program software. Results The world ASIR of cervical cancer and corpus uteri cancer were 9.76/100 000 and 8.54/100 000 respectively, and the world ASMR of cervical cancer and corpus uteri cancer were 1.76/100 000 and 0.95/100 000 respectively during 2004-2013. The medians of the age when diseases occurred were 47 and 52 years. The cervical cancer mortality began to increase from age 30 years, while the corpus uteri cancer mortality began to increase from age 40 years. During the 10 years, the incidences of both cervical cancer and corpus uteri cancer were in increase, the average annual percent change rates were 2.97%(Z=3.134, 95%CI :0.8%-5.2%)and 2.03%(Z=1.804, 95%CI:-0.6%-4.8%) respectively, and the mortalities of both cervical cancer and corpus uteri cancer were in increase too, the average annual increase rates were 3.35% (Z=1.323, 95%CI:-2.4%-9.4%) and 14.33% (Z=4.626, 95%CI: 6.9%-22.2%)respectively. The overall mortality increase rates were 29.49% and 216.28%. Conclusions In Guangzhou, the mortality rate of cervical cancer was higher than that of corpus uteri cancer, but the mortality rate of corpus uteri cancer increased rapidly during 2004-2013. So it is necessary to pay close attention to corpus uteri cancer prevention and control and strengthen the related health education while conducting cervical cancer screening.