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左旋卡尼汀治疗不稳定型心绞痛疗效观察
引用本文:王殿华,笪应芬.左旋卡尼汀治疗不稳定型心绞痛疗效观察[J].解剖与临床,2007,12(6):410-411.
作者姓名:王殿华  笪应芬
作者单位:1. 上海市第二人民医院ICU
2. 上海市第二人民医院B超室
摘    要:目的:探讨左旋卡尼汀治疗不稳定性心绞痛的临床疗效.方法:86例不稳定性心绞痛患者随机分为两组,每组43例.在常规治疗基础上,治疗组应用左旋卡尼汀,对照组应用极化液.结果:心绞痛缓解有效率治疗组为93.02%,对照组心绞痛缓解有效率为65.12%(P<0.01);静息心电图缺血性ST段恢复有效率治疗组为76.74%,对照组为48.84%(P<0.01).结论:左旋卡尼汀辅助治疗不稳定性心绞痛的是一种安全有效的方法,它能改善缺血心肌的能量代谢.

关 键 词:心绞痛  左旋卡尼汀  能量代谢  左旋卡尼汀  辅助治疗  不稳定型心绞痛  疗效观察  Unstable  Angina  Pectoris  Treatment  Observation  能量代谢  缺血心肌  改善  安全  恢复  缺血性  静息心电图  效率  结果  极化液  对照组  应用  治疗组
文章编号:1671-7163(2007)06-0410-02
修稿时间:2007年1月11日

Clinical Observation on L-carnitine in the Treatment of Unstable Angina Pectoris
WANG Dian-hua,DA Ying-fen.Clinical Observation on L-carnitine in the Treatment of Unstable Angina Pectoris[J].Anatomy and Clinics,2007,12(6):410-411.
Authors:WANG Dian-hua  DA Ying-fen
Abstract:Objective:To investigate the clinical effects of L-carnitine in the treatment of unstable angina pectoris.Methods:Eighty-six patients with unstable angina pectoris were randomly divided into two groups, each group consisted of 43 cases.On the basis of conventional therapy, the patients from experimental group were administered L-carnitine, at the same time, those patients in control group were given GIK (glucose insulin-potasiun solution).Results:The total effective rates of relieved angina pectoris and improved ECG in treatment group were 93.02% and 76.74% respectively, nevertheless, that in control group were 65.12% and 48.84% respectively. There were significant difference between two group(P<0.01).Conclusion:Adjunctive therapy with L-carnitine for treating unstable angina pectoris might be safe and effective way, L-carnitine could improve the energy metabolism of the ischemic myocardium.
Keywords:Angina pectoris  L-carnitine  Energy metabolism
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