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In vitro cell quality of articular chondrocytes assigned for autologous implantation in dependence of specific patient characteristics
Authors:Jan M. Pestka  Hagen Schmal  Gian Salzmann  Jochen Hecky  Norbert P. Südkamp  Philipp Niemeyer
Affiliation:(1) Department for Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;(2) Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Hugstetter Str. 55, 79106 Freiburg, Germany;(3) Metreon Bioproducts GmbH, Freiburg, Germany;
Abstract:

Objective  

Autologous chondrocyte implantation (ACI) is a well-established therapeutic option for the treatment of cartilage defects of the knee joint. Since information concerning the cellular aspects of ACI is still limited, the aim of the present study was to investigate relevant differences between chondrocyte quality after in vitro cultivation and possible correlations with patient-specific factors.
Keywords:
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