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The economic burden of rotavirus hospitalization among children < 5 years of age in selected hospitals in Bangladesh
Institution:1. icddr,b, Dhaka, Bangladesh;2. Mathematical Modelling Group, Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Viet Nam;3. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom;4. Karolinska Institutet, Stockholm, Sweden;5. University of Strathclyde, Glasgow, Scotland, UK;6. Bangladesh Institute of Development Studies, Dhaka, Bangladesh;7. Deakin Health Economics, School of Health and Social Development, Deakin University, Geelong, Victoria, Australia;8. Centers for Disease Control and Prevention, Atlanta, GA, USA;9. John Hopkins University, Baltimore, MD, USA;10. School of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden
Abstract:BackgroundRotavirus is a common cause of severe acute gastroenteritis among young children. Estimation of the economic burden would provide informed decision about investment on prevention strategies (e.g., vaccine and/or behavior change), which has been a potential policy discussion in Bangladesh for several years.MethodsWe estimated the societal costs of children <5 years for hospitalization from rotavirus gastroenteritis (RVGE) and incidences of catastrophic health expenditure. A total of 360 children with stool specimens positive for rotavirus were included in this study from 6 tertiary hospitals (3 public and 3 private). We interviewed the caregiver of the patient and hospital staff to collect cost from patient and health facility perspectives. We estimated the economic cost considering 2015 as the reference year.ResultsThe total societal per-patient costs to treat RVGE in the public hospital were 126 USD (95% CI: 116–136) and total household costs were 161 USD (95% CI: 145–177) in private facilities. Direct costs constituted 38.1% of total household costs. The out-of-pocket payments for RVGE hospitalization was 23% of monthly income and 76% of households faced catastrophic healthcare expenditures due to this expense. The estimated total annual household treatment cost for the country was 10 million USD.ConclusionsA substantial economic burden of RVGE in Bangladesh was observed in this study. Any prevention of RVGE through cost-effective vaccination or/and behavioural change would contribute to substantial economic benefits to Bangladesh.
Keywords:Economic burden  Rotavirus gastroenteritis  Diarrhea  Costs-of-illness  Catastrophic health expenditure  Bangladesh
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