Assessing the optimal imaging modality in the diagnosis of jaw osteomyelitis. A meta-analysis |
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| Institution: | 1. Unit of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences;2. Unit of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Room No 142 Sushruta Hostel Trauma Centre BHU, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India;3. Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India;1. Oral and Maxillofacial Surgery Department, Queen Elizabeth University Hospital Glasgow, United Kingdom;2. University of Glasgow Medical School, Faculty of Life Sciences, United Kingdom;3. BAOMS Royal College of Surgeons of England, 35/43 Lincoln''s Inn Fields, London, United Kingdom;1. Unit of Oral and Maxillofacial Pathology, The School of Clinical Dentistry, Claremont Crescent, Sheffield S10 2TA, UK;2. Department of Oral and Maxillofacial Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Glossop Road, Sheffield S10 2JF, UK;1. Bartshealth NHS Trust, Royal London Hospital, Whitechapel, London, UK;2. Queen Mary University of London, UK;3. Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, Freiburgstrasse 4, 3010 Bern, Switzerland |
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| Abstract: | Osteomyelitis is an inflammatory infectious disease that affects bone and bone marrow. Histopathology remains the gold standard method for diagnosis, but imaging modalities also play an important role. We systematically reviewed five articles with comparative studies on plain films, computed tomography (CT) scan, magnetic resonance imaging (MRI), cone beam computed tomography (CBCT), positron emission tomography (PET), single photon-emission computed tomography (SPECT), scintigraphy, and SPECT/CT. Scintigraphy and SPECT/CT has the highest sensitivity of 100%. PET is only to be used in cases of follow up. Orthopantomography (OPG) is the most common initial diagnostic tool despite its low sensitivity. CT provides the necessary specificity needed for radionuclide imaging, which has the highest negative predictive value of 100% and a positive predictive value >95%. SPECT/CT with 100% sensitivity and 85% specificity can be considered as the imaging modality of choice for initial diagnosis and follow up. |
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| Keywords: | osteomyelitis imaging jaw CT MRI SPECT Scintigraphy CBCT OPG |
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