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重复测量设计的方法在慢性疾病疗效评价中的应用探讨
引用本文:陈静,邵明义,魏明,赵文,邱建利. 重复测量设计的方法在慢性疾病疗效评价中的应用探讨[J]. 辽宁中医杂志, 2012, 0(3): 442-443
作者姓名:陈静  邵明义  魏明  赵文  邱建利
作者单位:河南中医学院;河南中医学院第一附属医院
基金项目:国家“十一五”科技支撑计划(2007BA120B094)
摘    要:探讨重复测量设计与分析方法在中医药治疗慢性疾病临床疗效评价中的应用以及应用中应注意的问题;通过对目前常用临床研究方案进行分析,在传统方案的基础上,引进重复测量设计的方法。该设计方法既遵循了随机对照试验的基本思想,同时又考虑到某指标在不同时间点上的关联性或该指标随时间变化的趋势,为中医药治疗慢性疾病的临床疗效评价提供一个更为合理和客观的方法。

关 键 词:重复测量设计  中医药  慢性疾病  临床疗效评价

Analysis on Application of Repeated Measurement Design in Effect Evolution of Chronic Diseases
CHEN Jing,SHAO Ming-yi,WEI Ming,ZHAO Wen,QIU Jian-li. Analysis on Application of Repeated Measurement Design in Effect Evolution of Chronic Diseases[J]. Liaoning Journal of Traditional Chinese Medicine, 2012, 0(3): 442-443
Authors:CHEN Jing  SHAO Ming-yi  WEI Ming  ZHAO Wen  QIU Jian-li
Affiliation:1(1.Henan College of Traditional Chinese Medicine,Zhengzhou 45000,Henan,China; 2.The First Hospital Affiliated to Henan College of Traditional Chinese Medicine,Zhengzhou 45000,Henan,China)
Abstract:This paper studies the design and analysis method of repetitive measure in TCM therapy for chronic disease clinical efficacy evaluation and application of some important problems in application.Based on current clinical research scheme analysis,the basis of the traditional scheme,introduce the design methods of repetitive measure.This design method both followed the basic idea of randomized controlled trials,also consider the relevance of some indexes at different points or the tendency of changes with time,providing a more rational and objective method of the evaluation of clinical curative effect on treating chronic disease with Chinese medicine.
Keywords:repeated measurements design  traditional Chinese medicine  chronic disease  clinical effect assessment
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