Gastrointestinal stromal tumor of the prostate |
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Authors: | Van der Aa Frank Sciot Raf Blyweert Wim Ost Dieter Van Poppel Hendrik Van Oosterom Allan Debiec-Rychter Maria De Ridder Dirk |
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Institution: | Department of Urology, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium. |
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Abstract: | We present a unique case of an atypical prostate tumor in a 49-year-old man with acute urinary retention. Digital rectal examination revealed a large prostate with a parenchymal mass on the left side. Radiologic imaging showed a 14.2 x 9.6 x 14.0-cm prostatic mass and multiple liver metastases. A pathologic diagnosis of a prostatic gastrointestinal stromal tumor was made and was confirmed by molecular analysis. Therapy consisted of a tyrosine kinase inhibitor, resulting in prostate mass reduction. After 100 weeks, the patient was in good physical condition with a continuing partial response with a reduced mass volume and liver nodules. |
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