男性乳腺癌20例分析

目的：探讨男性乳腺癌的病因及影响预后的因素。方法：对我院１９８３ 年～１９９８ 年收治的２０例男性乳腺癌患者的临床资料和随访结果进行了分析，并结合国内外文献对男性乳腺癌的临床特点、病因和影响预后的因素进行了探讨。结果：有６ 例患者在发展成为症状明显的癌肿之前有乳腺发育。全组５ 年总生存率为６０ ％ ，淋巴结阴性者的５ 年生存率为８０ ％ ，淋巴结阳性者为５０ ％ 。结论：男性（ 特别是青年男性） 乳腺癌的发生与雌激素和男性乳腺发育有关。腋窝淋巴结转移情况是最重要的预后指标。

Analysis of 20 cases of breast cancer in males

Objective:To explore the etiology of male breast cancer and factors influencing prognosis.Methods:The clinical data and the follow up results of 20 male breast cancer patients treated in our hospital from 1983 to 1998 were analysed,and the clinical characters,etiologic aspects and prognostic factors were discussed combined with domestic and overseas literatures.Results:Gynecomastia was found in 6 patients before clinical carcinoma. The total 5 years survival rate was 60%,the 5 years survival rate was 80% and 50% in the patients with negative and positive axillary lymph nodes,respectively.Conclusions:The occurrence of breast cancer in males (special the young males)is related to estrogen and gynecomastia.The axillary lymph node status is the most important prognostic index.