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静脉注射普罗帕酮对慢性期心室起搏阈值的影响
引用本文:姚均迪,赵峰,蒋逸风,林晓耘,吴宰盛.静脉注射普罗帕酮对慢性期心室起搏阈值的影响[J].中国心脏起搏与心电生理杂志,2004,18(2):100-101.
作者姓名:姚均迪  赵峰  蒋逸风  林晓耘  吴宰盛
作者单位:解放军第411医院,上海,200081
摘    要:观察静脉注射 (简称静注 )单剂量普罗帕酮对慢性期心室起搏阈值的影响。安置起搏器 3个月后的患者 30例 ,随机单剂量静注普罗帕酮 70mg或 14 0mg,用相应的体外程控仪测试用药前后心室起搏阈值。结果 :固定脉冲宽度 (脉宽 )为 0 .5ms或 0 .4 9ms时 ,普罗帕酮 70mg组用药前、用药后即刻、30min、2h的起搏阈值分别为 0 .5 7± 0 .13,0 .5 1± 0 .12 ,0 .5 9± 0 .10 ,0 .5 4± 0 .11V ;14 0mg组分别为 0 .5 8± 0 .14 ,0 .5 4± 0 .13,0 .5 7± 0 .14 ,0 .5 2± 0 .12V。结论 :单剂量静注普罗帕酮对慢性期心室起搏阈值没有影响。

关 键 词:心血管病学  心脏起搏  普罗帕酮  起搏阈值
文章编号:1007-2659(2004)02-0100-02
修稿时间:2003年4月11日

Effect of Intravenous Propafenone on Chronic Ventricular Pacing Threshold
YAO Jun-di,ZAO Feng,JIANG Yi-feng,et al..Effect of Intravenous Propafenone on Chronic Ventricular Pacing Threshold[J].Chinese Journal of Cardiac Pacing and Electrophysiology,2004,18(2):100-101.
Authors:YAO Jun-di  ZAO Feng  JIANG Yi-feng  
Institution:YAO Jun-di,ZAO Feng,JIANG Yi-feng,et al.The 411th Hospital of PLA,Shanghai 200081,China
Abstract:A single intravenous dose of propafenone was administered to evaluate its effect on chronic ventricular pacing threshold. 30 patients ,who had permanent cardiac pacemaker implanted for 3 months ,were given a dose of 70mg or 140mg propafenone intravenously randomly. Pacing thresholds were tested before and after propafenone administrated using corresponding programmer. Results :The pacing threshold(at a constant pulse width of 0.5ms or 0.49 ms) before and immediately, 30 min,2 h after intravenous propafenone were 0.57±0.13,0.51±0.12,0.59±0.10,0.54±0.11 V in 70mg group and 0.58±0.14,0.54±0.13,0.57±0.14,0.52±0.12 V in 140mg one respectively(P>0.05). Conclusion: There is no significant effect of propafenone on chronic ventricular pacing threshold given intravenously.
Keywords:Cardiology  Cardiac pacing  Propafenone  Pacing threshold
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