Latent acute promyelocytic leukemia t(15;17)(q22;q12-21) and sarcoidosis: long-term cohabitation |
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| Authors: | Leymarie V Galoisy A C Falkenrodt A Natarajan-Ame S Dufour P Lessard M |
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| Affiliation: | Laboratory of Hematology, Hautepierre University Hospital, avenue Moliere, F-67098 Strasbourg Cedex, France. vincent.leymarie@chru-strasbourg.fr |
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| Abstract: | The association of sarcoidosis with hematological malignancies is a well-known phenomenon. To our knowledge, we report the first case involving sarcoidosis and acute promyelocytic leukemia (APL) t(15;17)(q22;q12-21). The major interest lies in the chronology of the two diseases: the APL demonstrated an unusual smoldering evolution, suggesting that pre-existing sarcoidosis may have a non-fortuitous immunological impact on leukemic clone proliferation. |
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| Keywords: | Sarcoidosis Latent leukemia Promyelocytic leukemia t(15 17)(q22 q12– 21) |
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