腹型肥胖与胰岛素抵抗的关系

目的　研究腹型肥胖与胰岛素抵抗的关系。方法　采用人体测量参数体重指数( BMI)和腰臀围比值 ( W/H)将体脂分布不同分为腹内型肥胖组、皮下肥胖组及非肥胖组。观察 3组间血糖、血浆胰岛素水平及胰岛素敏感性指数的差异。结果　非肥胖组的胰岛素敏感性指数为 1 .0时 ,皮下型肥胖组与腹内型肥胖组分别为 0 .74和 0 .63。结论　随着肥胖者体脂分布的逐渐异常 ,胰岛素敏感性指数依次下降 ,胰岛素抵抗加重 ,腹内型肥胖者尤为显著。

Relationship between Intra-abdominal Obesity and Insulin Resistance

Objective To find the relationship between intra abdominal obesity and insulin resistance. Methods According to body mass index(BMI) and waist to hip circumference(W/H), the subjects were classified into three groups: intra abdominal obesity, subcutaneous obesity and non obesity group. The differences in blood glucose, plasma insulin level and insulin sensitivity index (ISI) among the three groups were observed. Results When being 1.0 in non obesity group, ISI in subcutaneous obesity and intra abdominal obesity group is 0.74 and 0.63 respectively. Conclusion ISI decreased and insulin resistance increased with the abnormality of fat distribution in obese patients, especially for the abdominal visceral obese patients.