颅内动脉瘤破裂的临床特点及相关危险因素探讨

目的探讨未破裂颅内动脉瘤发生破裂的临床特点及相关危险因素。方法对184例颅内动脉瘤患者的临床资料采用卡方检验及Logistic多元回归模型,对破裂组(150例)和未破裂组(34例)各相关危险因素进行统计学分析。结果颅内动脉瘤破裂出血的首发症状多为头痛(82.0%)、头晕(81.3%),多见于40~60岁,男∶女为1∶1.2。以ACA最常见,AComA其次,ICA最低。单因素分析表明,年龄(P=0.010)、吸烟(P=0.032)、嗜酒(P=0.038)、糖尿病(P=0.022)、瘤直径的大小(P=0.040)与颅内动脉瘤破裂有显著相关性;多因素Logistic分析结果显示,年龄、糖尿病是动脉瘤破裂的独立危险因素。结论颅内动脉瘤破裂好发于40~60岁,首发症状以头痛、头晕为主。年龄、糖尿病是动脉瘤破裂的危险因素。年龄≤60岁可增加动脉瘤破裂的风险,相反,糖尿病能降低动脉瘤破裂的风险。

Clinical characteristic and risk factors for intracranial aneurysm rupture

Objective To investigate the clinical characteristic and risk factors of intracranial aneurysms rupture.Methods Total 184 patients suffered intracranial aneurysms,including rupture(n=150) and unruptured(n=34),were collected in this retrospective research.Chi-square test and Logistic regression model were used for multifactor analysis.Results The symptoms of rupture of intracranial aneurysms mainly are headache(82.0%),dizziness(81.3%).The rupture of intracranial aneurysms most occurs in patients aged 40 to 6...