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196例男性不育症患者的细胞遗传学分析
引用本文:钟慧军,陈银涛,霍正浩,赵巍,焦海燕,彭亮,徐方,墙克信. 196例男性不育症患者的细胞遗传学分析[J]. 宁夏医科大学学报, 2003, 25(5): 326-327
作者姓名:钟慧军  陈银涛  霍正浩  赵巍  焦海燕  彭亮  徐方  墙克信
作者单位:宁夏医学院生物学教研室 银川750004(钟慧军,陈银涛,霍正浩,赵巍,焦海燕,彭亮,徐方),宁夏医学院生物学教研室 银川750004(墙克信)
摘    要:目的:研究染色体异常与男性不育的关系。方法:用常规方法制备外周血淋巴细胞标本,并对196例男性不育患者进行染色体G显带核型分析,个别辅作C带分析。结果:检出异常核型73例,占全部被检者37.2%。其中性染色体异常69例,占全部被检者35.2%,占异常核型94.5%,嵌合体3例,占异常核型4.1%;常染色体异常4例,占全部被检者2.04%,占异常核型5.5%。结论:细胞遗传学分析对不育患者是一个重要的实验室诊断手段。

关 键 词:男性不育症 细胞遗传学 染色体异常 核型 外周血 淋巴细胞
文章编号:1005-8486(2003)05-0326-02
修稿时间:2003-05-07

Cytogenetic Analysis of 196 Male Infertility Patients
ZHONG Hui-jun,CHEN Yin-tao,HUO Zheng-hao,et al. Cytogenetic Analysis of 196 Male Infertility Patients[J]. Journal of Ningxia Medical College, 2003, 25(5): 326-327
Authors:ZHONG Hui-jun  CHEN Yin-tao  HUO Zheng-hao  et al
Abstract:Objective:To study the relationship between chromosome abnormality and male infecundity Methods:Peripheral blood lymphocyte chromosome specimens were prepared by routine technique and analyzed on G band and additionally on C band in few cases if necessary.Results:Out of 196 cases,73 cases(37.3% of total patients) showed abnormal karyotypes, among them,69 sexual chromosome abnormality (3 cases mosaic abnormality),4 cases autosome abnormality (5.5% of totality).Conclusion:Cytogenetic analysis is an important means to diagnose chromosome related disorders for the individuals suffering infertility.
Keywords:male infecundity  chromosome abnormality  cytogenetics  karyotype
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