| 降糖宁胶囊中人参皂苷Rgl、Re的含量方法学考察 |
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| 引用本文： | 刘莉,齐洋.降糖宁胶囊中人参皂苷Rgl、Re的含量方法学考察[J].黑龙江医药,2014,0(2):304-306. |
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| 作者姓名： | 刘莉 齐洋 |
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| 作者单位： | 刘莉(哈尔滨圣泰生物制药有限公司)；齐洋(哈尔滨圣泰生物制药有限公司)； |
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| 摘 要： | 目的：建立HPLC法测定降糖宁胶囊中人参含量的方法。方法：Packed ODS-A C18色谱柱（4.6 mm×250 mm，5μm），以乙腈-0.05％磷酸溶液（100：400）为流动相；检测波长为203nm，流速为1ml/min。结果：人参皂苷Rg1、人参皂苷Re进样量均在0.4μg～1.6μg范围内进样量与峰面积呈良好线性关系（r=0.9996）；方法的平均回收率：人参皂苷Rg1为98.68%，RSD为1.71%（n=9）；人参皂苷Re为100.81%，2.71%（n=9）。结论：通过采用本方法对降糖宁胶囊人参中（Rg1、Re）的含量进行测定，方法准确可行，灵敏度高，能够有效控制产品质量。
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| 关 键 词： | 降糖宁 Rgl Re HPLC |
Methodological Study on Ginsenoside Re in Contents of Ginsenoside Rgl,Jiangtangning Capsules |
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| Institution: | Liu Li, et al (Harbin Sanctity Pharmaceutical Co., Ltd.) |
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| Abstract: | 0bjective：To establish the determination methods of ginsenoside Rg1, ginsenoside Re In Jiangtangning capsules by HPLC. Methods：A Packed ODS-A Cl8 column（4.6mm ×250mm,5μm）, Acetonitrile-0.05%phosphoric acid solution （100：400） as the mobile phase. The detection wavelength was 203nm.The flow rate was 1 ml/min. Results：The linear range of ginsenoside Rg1, ginsenoside Re were both 0.4~1.6μg （r=0.9996）. The average recovery of the method：ginsenoside Rg1 was 98.68%, RSD was 171%（n=9）;ginsenoside Re 100.81%, 2.71%（n=9）. Conclusion：the content was determined by the method of ginsenoside Rg1, ginsenoside Re in Jiangtangning capsules, the methods are accurate, high sensitivity, and can effectively control the quality of the products. |
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| Keywords: | Jiangtangning capsules ginsenoside Rgl ginsenoside Re HPLC |
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