无心畸形胎儿三例临床病理分析并文献复习

目的观察无心畸形胎儿的临床病理特点,并对其发生进行分析。方法对3例无心畸形胎儿的临床表现、外形和内脏结构以及胎盘形态进行观察与分析。结果 3例无心畸形胎儿均来自于双胎,均为无头和单体腔,可见发育不良的肠管,以及肾脏,其他脏器为：性腺与内生殖器1例,肾上腺和胰腺1例,胎盘为单绒毛膜型,2例有大血管吻合,均为单脐动脉。结论无心畸形胎儿有多种形态,其发生与双胎胎盘的血管吻合有密切关系。

Acardia fetus:a clinicopathologic study of 3 cases

Objective: To observe the clinicopathologic features of acardia and to study the pathogenesis of acardia.Methods: 3 cases of acardia were observed with analyses of clinical features,their extemalities and the structures of viscera and placentas.Results: 3 cases of acardia were all from twins.All of the three cases were acephalus and mono-coelome,there were dysplastic intestines and kidney,Other organ include gonad and sex organ in 1 case,adrenal gland and pancreatic gland in 1case.All of the placentas were in monochorial type and had dominant anastomoses and single umbilical artery.Conclusions: The various morphology of acardia could be observed the pathogenesis of acardia may be related with the anastomoses of the placenta.