软骨黏液样纤维瘤临床影像学表现及病理分析

目的　探讨软骨黏液样纤维瘤临床影像学表现及病理组织学特征 ,提高鉴别诊断。方法　 8例软骨黏液样纤维瘤均行X线检查 ,其中 4例行CT检查 ,8例均手术及病理证实 ,分析其影像学及病理表现。结果　肿瘤位于长骨干骺端 ,呈圆形或椭圆形透明区 ,其内密度均匀 ,与患骨长轴一致 ,内有骨嵴 ,周围有硬化骨 ,CT值为 2 6HU左右。病理组织学为分叶状 ,灰白色 ,略透明似软骨 ,小叶中心黏液丰富 ,有星形细胞 ,周边区为增生带 ,有多核巨细胞、软骨母细胞及纤维母细胞。结论　软骨黏液样纤维瘤的影像学和病理组织学方面均有特征性 ,但极易误诊。

Chondromyxoid Fibroma: Imaging Manifestations and Pathological Analysis

Objective To study the imaging findings and patholoical characterizes of chondromyxoid fibroma in order to improve its differential diagnosis.Methods 8 cases with chondromyxoid fibroma had all proceeded x-ray checked before operation. Of these cases , 4 cases were examed by CT scan .All cases were confirmed by operation and pathology. The imaging findings and pathological characterizes were analysed.Results The lesions located at metaphysis of long bone and presented as a round or elliptic transparent area which were consistent with long axis of involved bone. There were osseous crests inside the lesions and sclerosis bone around the lesions. The density of lesions was homogeneous and CT numbers were about 26 HU. On histopathology,lesions presented grey. Lobular and some what transparent . In the center of lesions there were a lots of mucus and stellate cells. The lesions were surrounded by hyperplastic area including multinuclear giant cell and chondroblast fibroblast. Conclusion chondromyxoid fibroma has characterizes on imagiology and pathology , but it has often been misdiagnosed.