女性生殖道支原体感染的研究进展

支原体是介于细菌和病毒之间无细胞壁能独立生存的最小微生物.其感染女性生殖道可引起多种疾病及母婴不良的妊娠结局.但近年来有关其致病性、检测的必要性、混合感染问题、药物治疗仍存在着争议.近年来支原体研究的结果显示,虽然支原体已趋于非致病菌、致病作用有限或属条件致病菌,但对于特殊人群及难治性生殖道感染等患者仍有必要检测及治疗,同时注意混合感染问题.支原体感染后与宿主细胞的相互作用,尤其是其对人体免疫系统的影响及治疗后耐药菌的出现及耐药菌株的检测将成为今后研究的方向.

Progress in research on mycoplasma infection in female reproductive tract

Mycoplasma is the smallest microorganism which lives without cell wall and is between bacteria and virus.Its infection in the female reproductive tract can cause many diseases and adverse outcomes of the pregnant women and the baby.But pathogenicity of mycoplasma,necessity of detection of it;co-infection and pharmacotherapy all are controversial in recent years.The recent research results suggested that it is necessary to examine and treat those special population or refractory reproductive tract infection,also,co-infection should be considered although mycoplasma trends to become a non-pathogen or a conditional pathogen or it has limited pathogenicity.The mutual actions of the patient and infected mycoplasma,specially influences on immune system,development of drug-resistant strains after treatment and detection of those drug-resistant strains will become hot-spot of the research in future.