罗比卡因与布比卡因用于小儿术后镇痛的比较

目的比较相同浓度的罗比卡因与布比卡因用于小儿硬膜外术后镇痛的镇痛效果和并发症。方法选择60例行腰硬联合麻醉的腹部手术患儿随机分成两组行硬膜外术后镇痛，A组用0．1％罗比卡因，B组用0．1％布比卡因，每组分别复合芬太尼2ug/ml，镇痛泵容量为100ml，泵速为2ml／h，维持镇痛时间48h。观察指标有运动神经阻滞评分、手术后各时段的SpO：、BP、HR，OPS法镇痛效果评分、并发症情况。结果A组和B组比较，下肢运动阻滞程度两者相比差异有统计学意义（P〈0．05），手术后观察各时段的SpO2、BP、HR，两者相比无显著性差异，OPS法镇痛效果评分两者相比差异无显著性（P〉0．05），并发症两者相似（P〉0．05）。结论0．1％罗比卡因复合芬太尼2us／ml具有同0．1％布比卡因复合芬太尼2us／ml同样的镇痛效应，而且对运动神经影响轻微，有利于患儿早期下床活动，用于小儿术后镇痛值得推广。

To compare the differences in analgesia effect and complication of the same concentrated ropivacaine and Bupivacaine after epidural anaesthesia in children

Objective To compare the differences in analgesia effect and complication of the same concentrated ropivacaine and Bupivacaine after epidural anaesthesia in children. Methods Divide 60 children randomly into group A and group B ,perform anagesia after epidural anaethesia with 0.1%ropivacaine in group A and 0.1% Bupivacaine in group B.Pump Fentanyl 2 ug/ml with the speed of 2 ml/h and the total dosage of 100 ml in 48 h simultaneously. The observation index includes motor nerve block score/SpO2,BP,HR in different periods after operation、anagesia effect score of OPS and complication. Results It has a significant difference in inferior extremity motor nerve block(P<0.05) , no difference in SpO2,BP,HR in different periods after operation ,and similarity in complication(P>0.05) between the two groups. Conclusion 0.1% ropivacaine has the same level of anagesia effect as 0.1% Bupivacaine combinated by Fentanyl 2 ug/ml,and it has smaller influence on motor nerve.It is profit for children' early ambulation,so it is worth of generalization.