乳酸亚铁片治疗缺铁性贫血的临床疗效

目的观察乳酸亚铁片治疗缺铁性贫血(IDA)的疗效和不良反应。方法采用随机对照的试验方法,将乳酸亚铁治疗IDA的疗效及不良反应与琥珀酸亚铁进行比较,疗程6周。结果乳酸亚铁片治疗4周的显效率、有效率及总有效率分别为72.41%、17.24%和89.65%,而琥珀酸亚铁的则分别为54%、22%和76%,前者疗效优于后者(P<0.05),显示乳酸亚铁片治疗IDA见效较琥珀酸亚铁快;乳酸亚铁治疗IDA6周的显效率及有效率分别为93.05%和2.78%,而琥珀酸亚铁的则分别为93.44%和4.92%,无统计学差异(P>0.05),显示两药治疗6周的疗效基本相同。两药不良反应比较无明显差异(P>0.05)。结论乳酸亚铁片治疗IDA疗效好,胃肠不良反应轻,患者耐受性好,是治疗IDA安全、有效的口服铁剂。

The effectiveness and side effects of Ferrous Lactate tablets for patients with iron deficiency anemia

OBJECTIVE To study the treatment effectiveness and side effects of Ferrous Lactate tablets for the patients with iron deficiency anemia (IDA). METHODS A randomized clinical trial was performed to compare the treatment effectiveness and side effects of Ferrous Lactate tablets with Ferrous Succinate tablets on patients with IDA orally taken for 6 weeks. RESULTS On the forth week of the trial, remarkably effective rate, effective rate and totally effective rate of ferrous lactate and ferrous succinate were 72.41%,17.24%,89.65% and 54%,22%,76%, respectively. The effectiveness of ferrous lactate was higher than that of ferrous succinate (P<0.05). The remarkably effective rate and effective rate of ferrous lactate and ferrous succinate on the sixth week of the trial were 93.05%, 2.78% and 93.44%, 4.92%, respectively. The effectiveness of two drugs was the same(P>0.05).while the side effects of both drugs were no difference (P>0.05). CONCLUSION Ferrous Lactate tablet is a highly effective drug as Ferrous succinate tablets and with endurably mild side effects to patients with IDA.