脱细胞猪真皮基质覆盖治疗人深Ⅱ度烧伤

目的研究应用脱细胞猪真皮基质（以下简称基质）一次性覆盖治疗人体深Ⅱ度烧伤的方法及效果。方法对1998年1月-2002年1月在我院住院治疗的128例烧伤患者的治疗方法与效果进行总结分析。对深Ⅱ度偏浅创面,用新洁尔灭液冲洗受伤皮肤,去净表皮,用浸过碘伏液的基质覆盖,纱布绷带包扎。对深Ⅱ度偏深创面,行削痂术削到间生态层,用基质覆盖,纱布绷带包扎。结果128例全部治愈,均得到满意的临床效果。结论基质是一种良好的促进创面上皮化的生物敷料,用其一次性覆盖创面、中途不换药治疗深Ⅱ度烧伤是可行的,可使病人休克期及整个疗程病情稳定,并发症减少,病程缩短。

Porcine acellular dermal matrix in the treatment of deep partial-thickness burns in human

Objective To investigate the possibility of treating deep partial-thickness burns by closed dressing of the wounds with porcine acellular dermal matrix (ADM) and evaluate the therapeutic effects. Methods We conducted a retrospective review of 128 cases of bum patients who received treatment with porcine ADM within the period from January 1998 to January 2002 in our hospital. Different procedures were adopted according to the degree of the bum injury. As for "fairly superficial" deep partial-thickness skin bums, after removing the necrotic epidermis and washing with 0.1% benzalkonium bromide, the wound was covered with porcine ADM pretreated with povidone-iodine and then bandaged with cotton gauze and bandages. In cases of "fairly deep" deep partial skin thickness burns, eschar excisions as deep as to expose parabiotic lamina were performed prior to dressing the wounds in the same manner as described above. Results All the patients were successfully treated with satisfactory clinical results. Conclusions Porcine ADM is feasible as an efficient dressing material for deep partial-thickness burns, which may promote epithelialization in the wounds and help stabilize the patients' condition during bum shock stage to reduce the complications and shorten the treatment courses.