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门静脉系统插管化疗的实验研究
引用本文:周振理. 门静脉系统插管化疗的实验研究[J]. 天津医药, 1991, 19(11): 658-660
作者姓名:周振理
作者单位:天津市南开医院第一外科,日本神户大学第一外科
摘    要:

关 键 词:肝肿瘤 药物疗法 门静脉插管

Experimental Study on Catheterized Chemotherapy in Portal Vein System
Zhou Zhenli,et al Tianjin Nankai Hospital. Experimental Study on Catheterized Chemotherapy in Portal Vein System[J]. Tianjin Medical Journal, 1991, 19(11): 658-660
Authors:Zhou Zhenli  et al Tianjin Nankai Hospital
Abstract:Implanted Vx-2 tumors in rabbit's livers were treated only by chemotherapyof Adriacin(0.5mg/kg/day)through the portal vein system,using implantable druginjection device(Port-A-Cath-System,PACSO).After 5 days of treatment,the tumorvolume proliferation folds of treated group was much smaller than that of thecontrol group(P<0.01)and the depression rate of tumor proliferation was higherthan 42%(54.5%),indicating effectiveness.Neither surgical complications nor liverfunction damage were found.The pathophysiologic basis and importance of clinicapplication of this approach of therapy were also discussed.
Keywords:hepatic tumor  local chemotherapy  catheterization of portal vein  
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