内镜治疗109例恶性胆道梗阻的临床分析

目的探讨经内镜治疗恶性胆道梗阻的临床应用价值。方法回顾分析近4年来经内镜治疗恶性胆道梗阻患者109例的临床资料，并进行生存率分析。结果操作成功率94．8％，减黄总体有效率89．9％，内镜治疗后1周肝功能明显好转，术后并发胰腺炎4例（3．7％）、胆管炎2例（1．8％）；ERBD术后3个月、6个月及1年的预计存活率分别为83．6％、69．1％及28．8％，EMBE术后3个月、6个月及1年的预计存活率分别为96．4％、80．4％及36．3％，两组存活率差异无统计学意义。结论对于无法实行根治性手术的恶性胆道梗阻患者采取经内镜下介入治疗不失为一种安全有效的治疗方案。

Endoscopic treatment for malignant biliary obstruction:a report of 109 cases

Objective To evaluate the efficacy of endoscopic treatment for malignant biliary obstruction.Methods Retrospective survival analysis was performed in 109 cases of malignant biliary obstruction that underwent endoscopic retrograde cholangiopancreatography(ERCP)in the past 4 years.Results The success rate of endoscopic procedure was 94.8%,and janndice reduction rate was 89.9%.Liver function was significantly improved at one week after endoscopic treatment.Procedure related complications included pancreatitis in 4(3.7%)and cholangitis in 2(1.8%).Life expectancy after endoscopic naso-bili-ary drainage(ENBD)at 3,6 and 12 months were 83.6%,69.1%and 28.8%,respectively,and those after endoscopic metal biliary endoprothesis(EMBE)were 96.4%,80.4%and 36.3%,respectively,between which there was no significant difference.Conclusion For malignant biliary obstruction that can not be radically resected.endoscopic treatraent is a safe and effective method.