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乙哌立松治疗顽固性呃逆
引用本文:傅文安. 乙哌立松治疗顽固性呃逆[J]. 中国新药与临床杂志, 2005, 24(4): 311-313
作者姓名:傅文安
作者单位:绍兴市人民医院,浙江,绍兴,312000
摘    要:目的:观察乙哌立松对顽固性呃逆的疗效及安全性。方法: 126例顽固性呃逆病人分为2组,其中治疗组66例(男性36例,女性30例)采用乙哌立松治疗。最小剂量50mg, tid,最大剂量100mg,tid。对照组60例(男性32例,女性28例),采用甲氧氯普胺、硝苯地平、东莨菪碱、氯丙嗪常规治疗。结果:治疗组总有效率92 %,对照组总有效率67 %,2组疗效比较差异有非常显著意义(P<0. 01)。治疗组服药d1起效率53 %,对照组为32% (P<0. 05)。治疗组疗程明显缩短,不良反应小。结论:乙哌立松对顽固性呃逆的治疗安全、有效。

关 键 词:呃逆  消化系统疾病  神经系统疾病  乙哌立松
文章编号:1007-7669(2005)04-0311-03
修稿时间:2004-11-10

Therapeutic effect of eperisone on intractable hiccup
FU Wen-an. Therapeutic effect of eperisone on intractable hiccup[J]. Chinese Journal of New Drugs and Clinical Remedies, 2005, 24(4): 311-313
Authors:FU Wen-an
Abstract:AIM: To observe the effect of eperisone on the intractable hiccup. METHODS: One hundred and twenty-six patients with intractable hiccup were randomly divided into two groups. The treatment group 66 patients were given eperisone with dosage from 50 mg, tid to 100 mg, tid, while the control group 60 patients were given metoclopramide, nifedipine, scopolamine, chlorpromazine. RESUITS:The total effective rate 92 % of the treatment group was remarkably higher than that of the control group 67 % (P< 0.01). One day's effective rate of treatment group (53 %) was also higher than that of the control group (32 %)(P<0.05). CONCLUSION:Eperisone therapy for intractable hiccup is safe and effective.
Keywords:hiccup  digestive system diseases  nervous system diseases  eperisone
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