总状土木香氯仿部位的化学成分研究

目的:研究总状土木香氯仿部位的化学成分。方法:采用硅胶、反相硅胶、SephadexLH-20凝胶柱色谱对样品进行分离纯化,根据理化性质和光谱分析鉴定化合物结构。结果:从总状土木香氯仿部位中分离得到6个化合物,经鉴定分别为11α,13-二羟基去氢闭鞘姜内酯(1)、11,13-二氢-7,11-去氢-13-羟基-3-脱氧愈创内酯C(2)、1β-羟基柯拉汀(3)、胡萝卜苷(4)、β-谷甾醇(5)、丁香树脂醇(6)。其中化合物1、2、3和6为首次从该属植物中分离得到。结论:本试验结果可为总状土木香的进一步研究提供依据。

Study on Chemical Constituents in Chloroform Part oflnula racemosa

OBJECTIVE： To study the chemical constituents of Inula racemosa. METHODS： The samples were separated and purified by silica gel, RP silica gel and Sephadex LH-20 gel column chromatography and the structures of chemical compound were analyzed and identified by physicochemical property and spectral analysis. RESULTS： Six compounds were obtained and identified as： 11 a, 13-dihydroxydehidrocostuslactone （1）, 11,13-dihydro-7, 11-dehydro-13-hydroxy-3-desoxyzaluzanin C （2）, 1 fl-hydroxyco- lartin （3）,fl-sitosterolglucoside （4）,fl-sitosterol （5）, syringaresinol （6）. Compounds 1, 2, 3 and 6 were isolated from the plant for the first time. CONCLUSION： The trial can provide reference for the further study of I. racemosa.