老年骨髓增生异常综合征的临床特征分析

目的：探讨老年骨髓增生异常综合征(MDS)的临床特点，以利于有效诊治。方法：回顾性分析23例老年MDS患者确诊时的形态学改变以及症状、体征、伴发疾病和初次治疗反应等临床资料。结果：老年MDS起病较为隐匿，所有患者均有不同程度病态造血，95．7％的患者发生贫血，其中21．8％为重度贫血；30．4％的患者白细胞减低，其中21.8％的患者血小板减低．78．3％的患者伴发其他疾病。常规治疗措施对本组患者疗效极差。结论：目前尚无早期诊断和有效治疗老年MDS的满意策略，呼吁重视此方面研究。

Analysis of the clinical characteristics of elderly patients with myelodysplastic syndrome

Objective:To discuss the clinical characteristics of elderly patients with myelodysplastic syndrome.Method:Clinical data of twenty three elderly patients with myelodysplastic syndrome were reviewed, including morphologic changes of hematologic cells, symptoms, physical signs, accompanied diseases, treatment protocol and effects.Result:Most of those patients hadn't obvious symptom in the initial stage. All the patients of this group had characteristics of ineffective hematopoiesis. 95.7% of those patients had anemia and 21.8% of them had severe anemia. 30.4% of those patients with leucocytopenia, 21.8% with thrombocytopenia and 78.3% accompanied with other diseases were also been found. The effects of common therapies were frustrated.Conclusion:There still has no satisfied strategy for elderly patients with myelodysplastic syndrome about early diagnosis and effective treatment.