| 3种抗癫痫药的血药浓度监测及个体化用药体会 |
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| 引用本文： | 李红健,冉国侠,曹丽蒙,吴建华.3种抗癫痫药的血药浓度监测及个体化用药体会[J].中国药房,2001,12(3):160-161. |
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| 作者姓名： | 李红健 冉国侠 曹丽蒙 吴建华 |
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| 作者单位： | 新疆自治区人民医院药 剂科, |
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| 摘 要： | 目的 :为临床抗癫痫药的合理应用提供参考。方法 :采用荧光偏振免疫法对88例服用苯妥英钠、63例服用苯巴比妥和63例服用卡马西平的患者进行血药浓度监测242次 ,并提供个体化给药方案。结果 :癫痫患者对这3种抗癫痫药的敏感性个体差异很大。结论 :癫痫患者的个体化用药必须以血药浓度数据为依据 ,还需综合考虑其他方面的因素
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| 关 键 词： | 苯妥英钠 苯巴比妥 卡马西平 血药浓度监测 个体化给药 |
| 文章编号： | 1001－0408（2001 ）03－0160－02 |
| 修稿时间： | 2000年11月20 |
Depermination of the Serum
Concentrations of Three Kinds of Antiepileptic Drugs and the Experience of Individualized
Drug Administration |
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| LI Hongjian,RAN Guoxia,CAO Limen,WU Jianhua.Depermination of the Serum
Concentrations of Three Kinds of Antiepileptic Drugs and the Experience of Individualized
Drug Administration[J].China Pharmacy,2001,12(3):160-161. |
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| Authors: | LI Hongjian RAN Guoxia CAO Limen WU Jianhua |
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| Abstract: | AIM:To give some information for rational administration of oral antiepileptic drugs to epileptic patients in clinic METHODS:The serum concentrations of oral phenytoin sodium,phenobarbital and carbamazepine were determined in 88,63 and 63 epileptic patients(total 214 times)by fluorescence polarization immunoassay,respectively The individualized drugs administration schemes were provided RESULTS:The sensitivity to the three kinds of antiepileptic drugs varied in different patients CONCLUSIONS:The administration of oral antiepileptic drugs to epileptic patients must be based on the data of drug concentration in serum We must comprehensively consider the other factors |
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| Keywords: | phenytion sodium phenobarbital carbamazepine determination of serum drug concentration individualized drug administrration |
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