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Transmetatarsal Amputation in the Setting of Antiphospholipid Antibody Syndrome
Authors:Jacob M McLeod  Charles O Brantigan  Kristen Alix  Dustin L Kruse  Paul A Stone
Institution:1. First Year Resident, Highlands-Presbyterian/St. Luke''s Podiatric Medicine and Surgery Residency Program, Denver, CO;2. Attending Vascular Surgeon, Presbyterian/St. Luke''s Medical Center, Denver, CO;3. Attending Vascular Nurse Practitioner, Presbyterian/St. Luke''s Medical Center, Denver, CO;4. Director of Research, Highlands-Presbyterian/St. Luke''s Podiatric Medicine and Surgery Residency Program, Denver, CO;5. Program Director, Highlands-Presbyterian/St. Luke''s Podiatric Medicine and Surgery Residency Program, Denver, CO
Abstract:Antiphospholipid syndrome is a hypercoagulable disease that can present foot and ankle surgeons with a unique challenge in treating patients who present with thrombosis and ischemia despite having normal pedal pulses. Appropriate perioperative management is imperative in these patients, because limb- and life-threatening complications can occur postoperatively, despite aggressive anticoagulation. We present the case of a 46-year-old male who underwent a transmetatarsal amputation and, despite aggressive therapy, developed a myriad of complications postoperatively. At 10 months postoperatively, the patient was doing well in an accommodative orthotic with minimal pain while receiving continued aggressive therapy and follow-up examinations by a number of specialists to treat his antiphospholipid syndrome.
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