1. Department of Microbiology, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA;2. Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA;3. Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA;4. Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA;5. Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University, 130-701 Seoul, Korea
Abstract:
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Highlights? Nearly half of all 75 TRIM protein family members are innate immune enhancers ? TRIM mRNA expression and protein localization are complexly regulated during infection ? TRIMs confer differential regulation in distinct innate immune signaling pathways
