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Oncocytoma of the adrenal gland medulla
Authors:Marcela Chisté  Robert J. Poppiti  Fernando J. Bianco
Affiliation:1. Department of Pathology, Mount Sinai Medical Center, Miami Beach, FL 33140, USA;2. Department of Urology, Columbia University, New York, NY 10032, USA;1. Service de chirurgie maxillo-faciale et stomatologie, CHU d’Angers, 4, rue Larrey, 49033 Angers cedex 01, France;2. Service de chirurgie maxillo-faciale et plastique de la face, CHU Trousseau, route de Loche, 37044 Tours cedex, France;1. Piracicaba Dental School, University of Campinas, Piracicaba, Brazil;2. School of Dentistry, State University of Western Paraná, Cascavel, Brazil
Abstract:We report an unprecedented case of an oncocytoma of the adrenal gland medulla in a 61-year-old woman. The patient presented with right flank pain and hematuria. Computed tomographic studies revealed a right adrenal gland mass that measured 2 cm, which was subsequently excised laparoscopically. Grossly, the tumor in the medulla measured 1.9 × 1.2 cm, weighed 5 g, and had a solid tan-brown cut surface. Histologically, it consisted of large tumor cells containing eosinophilic granular cytoplasm arranged in trabecular and nodular patterns. Electron microscopy revealed closely packed mitochondria in the cytoplasm of almost all tumor cells. The tumor cells were immunohistochemically positive for vimentin. The patient resumed usual activities 2 weeks after surgery, and at 6-month follow-up, she is doing well.
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