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Synthesis and Anticonvulsant Activity of N-Substituted 4-Amino-3-Nitrocoumarins
Authors:Mokrov  G. V.  Savel’ev  V. L.  Voronina  T. A.  Litvinova  S. A.  Kovalev  I. G.  Nerobkova  L. N.  Dmitrienko  A. O.  Gudasheva  T. A.  Seredenin  S. B.
Affiliation:1.V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences, 8 Baltiiskaya St., Moscow, 125315, Russia
;2.A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilova St., Moscow, 119991, Russia
;
Abstract:Pharmaceutical Chemistry Journal - The synthesis and anticonvulsant activity of new coumarin derivatives are reported. N-(3-Nitrocoumarin-4-yl)-4-aminobutyric acid (1a) at doses of 60 and 80 mg/kg...
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