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Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors |
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| Authors: | Ciccone Lidia Nencetti Susanna Camodeca Caterina Ortore Gabriella Cuffaro Doretta Socci Simone Orlandini Elisabetta |
| Affiliation: | 1.Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy ;2.Research Center “E. Piaggio”, University of Pisa, 56122, Pisa, Italy ;3.Department of Earth Sciences, University of Pisa, Via Santa Maria 53 – 55, 56100, Pisa, Italy ; |
| Abstract: | Pharmaceutical Chemistry Journal - Transthyretin (TTR) is a homo-tetrameric protein characterized by four identical β-sheet rich monomers assembled together to form a tetramer that is crossed,... |
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