输血传播肝炎的流行病学研究

本文用ELISA法对224例住院输血病例进行了半年乙肝病毒感染指标的随访研究,并对发生病毒性肝炎的患者进行了病原学分型诊断。结果输血后肝炎的发病率是3.13%(7例),其中乙型肝炎占28.57%(2例),非甲非乙型肝炎占71.43%(5例)。输血后HBV感染率为9.38%(21例),其中有6例在输血后5~6个月时出现抗-HBs。输血后肝炎病例绝大多数(6例)起病缓慢,且发展成慢性肝炎,仅1例在随访期间痊愈。本文作者提出应该用更敏感的方法代替RPHA,对献血员进行HBV感染指标的检测。

An Epidemiological Study on the Post-Transfusion Hepatitis

The incidence of post-transfusion hepatitis (PTH) was investigated in 224 hospitalized patients with 6 months follow-up study by using ELISA. The results showed that the incidence rate of PTH was 3.13% (7 cases). Among them hepatitis B was 28.57% (2 cases) and NANB hepatitis was 71.43% (5 cases). The infection rate HBV was 9.38% (21 cases), The anti-HBs antibody were detected after 5-6 months of transfusion in 6 of the 21 cases. The onset of all the cases of PTH was gradul the disease developed chronic hepatitis. Only one case was recovered during the follow-up period. The authors indicated that the more sensitive method should be used to detected the HBV in the blood donors instead of RPHA.