| 一阶导数光谱法测定盐酸哌甲酯片含量及含量均匀度 |
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| 引用本文： | 赵勤,周忆新. 一阶导数光谱法测定盐酸哌甲酯片含量及含量均匀度[J]. 抗感染药学, 2006, 3(1): 28-29 |
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| 作者姓名： | 赵勤 周忆新 |
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| 作者单位： | 江苏省苏州药品检验所,江苏,苏州,215002;江苏省苏州药品检验所,江苏,苏州,215002 |
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| 摘 要： | 目的:建立一阶导数光谱法测定盐酸哌甲酯片含量及含量均匀度的方法。方法:以水为溶媒用一阶导数光谱法测定盐酸哌甲酯片的含量及含量均匀度。结果:盐酸哌甲酯的平均回收率为:99.12%,RSD为:0.60%。结论:该方法简便、快速、准确。
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| 关 键 词： | 盐酸哌甲酯片 一阶导数光谱法 含量测定 含量均匀度 |
| 文章编号： | 1672-7878（2006）01-0028-02 |
| 收稿时间： | 2005-05-18 |
| 修稿时间： | 2005-07-06 |
Determination of Content and Content Uniformity of Methylphenidate Hydrochloride Tablets by First Derivation Spectrophotometry |
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| ZHAO Qin,ZHOU Yi-xin. Determination of Content and Content Uniformity of Methylphenidate Hydrochloride Tablets by First Derivation Spectrophotometry[J]. Anti-infection Pharmacy, 2006, 3(1): 28-29 |
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| Authors: | ZHAO Qin ZHOU Yi-xin |
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| Affiliation: | Jiangsu Suzhou Institute for Drug Control, Suzhou Jiangsu 215002,China |
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| Abstract: | Objective: To establish a more simple and rapid method for determining the content and its uniformity of methylphenidate hydrochloride tablets. Methods: The first derivation spectrophotometry method was used to determine the content and content uniformity of methylphenidate hydrochloride tablets with the solvent of water. Results: The average recovery was 99.12 %,with 0.70 % RSD.The linear range was 0.12~0.60 mg/mL. Conclusion: The method is simple, rapid and accurate. |
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| Keywords: | Methylphenidate hydrochloride tablets First derivation spectrophotometry Assay Content uniformity |
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