空气污染与儿童哮喘发病机制的研究进展

我国多地区雾霾严重,空气质量堪忧。大气污染成因复杂,大气颗粒物的来源更为复杂多变。常见的空气污染物种类繁多,如交通相关空气污染物、多环芳香烃、香烟烟雾、尘埃颗粒及细颗粒物 PM2.5,均与儿童哮喘密切相关,其毒性组分和致毒机制尚不明确,健康效应和毒理机制已经成为前沿的科学热点问题之一。本文就近几年来关于空气污染加重或引起儿童哮喘的机制进行综合分析。

Research progress on the relationship between air pollution and mechanism of asthma in children

At present,the smog is serious and the air is of poor quality in many parts of China.The causes of air pollution are complicated.The sources of atmospheric particulates are more complex and variable. A wide variety of air pollutants are common, such as traffic related air pollutants, polycyclic aromatic hydrocarbons, cigarette smoke, dust particles and fine particles PM 2.5. And these pollutants are all closely related to childhood asthma. However, the toxic components and toxic mechanisms of them have not been confirmed.In addition, the health effects and toxicological mechanisms have become one of the hot issues in the scientific frontier.In this paper, the mechanism of air pollution on causing or aggravating asthma in children in recent years was analyzed comprehensively.