慢性闭角型青光眼眼压控制稳定后视野变化规律的初步观察

目的观察慢性闭角型青光眼眼压稳定于正常水平(＜21 mmHg)(1 mmHg=0.133 kPa)后视野的变化情况,探讨慢性闭角型青光眼视神经病损的可能变化规律.方法收集1998年1月～2003年10月间在北京协和医院眼科诊治、经手术治疗后眼压控制至正常水平的慢性闭角型青光眼病例,共计29例47眼,所有患者均需于眼压稳定后行Humphrey视野计24-2程序行视野检查至少两次,间隔时间至少1年以上,并按照随访时间长短将所有观察对象分为两组,即l～2年组和2年以上组.根据进展期青光眼干预研究(AGIS)的标准进行视野评分及秩和检验;将视野分为五个区域并计算每个区域的光敏感度和缺损深度.结果随诊1～2年和2年以上患者视野的AGIS评分、各区缺损深度及各区光敏感度差异均无显著性(P＞0.05).结论慢性闭角型青光眼患者眼压稳定于正常水平时,其青光眼视神经病损可能无明显进展.

Visual fields changes in chronic angle closure glaucoma patients after their intraocular pressures were well controlled

Objective To investigate the progression of visual field loss and to explore the prognosis of glau-comatous optic neuropathy in patients with chronic angle-closure glaucoma (CACG) after their intraocular pressures were well controlled under 21 mmHg. Methods Forty-seven eyes of 29 patients in the Department of Ophthalmology in PUMC Hospital were included. All the patients had at least two separate tests of visual fields using the 24-2 program of the Humphery Visual Field Analyzer after their intraocular pressure were well controlled under 21 mmHg after sugery. The visual fields of patients were followed routinely for at least 1 year. In addition, all patients were divided into 2 groups according to follow-up period: 1-2 years group and over 2 years group. Visual field scores were calculated with the Advanced Glaucoma Intervention Study (AGIS) method. The visual fields were divided 5 sections and the sensitivity and defect depth of each section were calculated. Result No statistically significant differences were found in terms of AGIS scores, localized sensitivities and localized defects within the time interval of the observation. Conclusion Glaucomatous optic neuropathy is not likely to progressively deteriorate in CACG cases once their intraocular pressure are well controlled under 21 mmHg.