|
|||||
|
|
| Protein Kinase Activity of Phosphoinositide 3-kinase Regulates-adrenergic Receptor Endocytosis | |
| 摘 要： | Phosphoinositide3-kinase(PI(3)K)isauniqueenzymecharacterizedbybothlipidandproteinkinaseactivities.Here,wedemonstratearequirementfortheproteinkinaseactivityofPI(3)Kinagonist-dependent-adrenergicreceptor(βAR)internalization.UsingPI(3)Kmutantswitheitherproteinorlipidphosphorylationactivity,weidentifythecytoskeletalproteinnon-muscletropomyosinasasubstrateofPI(3)K,whichisphospho- |
| 本文献已被 CNKI 等数据库收录！ | |