环孢素A联合纳洛酮治疗重型颅脑损伤疗效分析

目的探讨环孢素A联合纳洛酮治疗重型颅脑损伤的临床疗效。方法将64例重型颅脑损伤患者分为观察组和对照组,对照组给予常规治疗,观察组在此基础上给予环孢素A联合纳洛酮治疗,观察两组患者预后及死亡情况。结果观察组意识觉醒时间早于对照组(P<0.05);观察组死亡率低于对照组(P<0.05);观察组治疗后GCS评分高于对照组(P<0.05)。结论环孢素A联合纳洛酮对改善重型颅脑损伤患者的预后有积极意义。

Efficacy analysis of cyclosporine A and naloxone on the treatment of severe traumatice brain injury

Objective To investigate the clinical efficacy of cyclosporine A and naloxone on the treatment of servere traumatic brain injury.Methods 64 cases of severe traumatic brain injury were divided into the observation group and the control group.The control group was treated with conventional method,while the observation group was additonally treated with cyclosporine A and naloxone.The observations were carried out with prognosis and death conditions of both groups.Results The awakening time of the observation group was earlier than that of the control group (P < 0.05).And the death rate of the observation group was lower than that of the control group(P < 0.05).After treatment,the GCS of the observation group was higer than that of the control group (P < 0.05).Conclusion Cyclosporine A and naloxone have positive effects on the improvement of prognosis of servere traumatic brain injuries.