卵巢子宫内膜异位囊肿腹腔镜手术对卵巢储备功能影响的研究

目的探讨卵巢子宫内膜异位囊肿腹腔镜手术治疗对卵巢储备功能的影响。方法选择2008年6月～2010年6月住院的卵巢子宫内膜异位囊肿实行腹腔镜手术的患者80例,其中单侧卵巢子宫内膜异位囊肿37例患者作为A组;双侧卵巢子宫内膜异位囊肿43例患者作为B组。选择单侧卵巢畸胎瘤腹腔镜手术患者35例为对照组,比较各组手术前后血清黄体生成激素、雌二醇、卵泡刺激素的变化,随访患者术后6个月及术后1年基础FSH的恢复情况。结果与患者术前血清激素水平比较,术后B组卵泡刺激素明显增高,雌二醇明显下降,黄体生成激素明显下降,差异有统计学意义(P<0.05)。与患者术前血清激素水平比较,A组和对照组术后各激素水平差异均无统计学意义。术后,与对照组比较,B组卵泡刺激素明显增高,雌二醇明显下降,黄体生成激素明显下降,差异有统计学意义(P<0.05)。结论腹腔镜手术对双侧卵巢子宫内膜异位囊肿的卵巢储备功能有一定影响。

Study on the effect of laparoscopic surgery of ovarian endometrioma on ovarian reserve function

Objective To study the effect of laparoscopic surgery of ovarian endometrioma on ovarian reserve function.Methods 80 cases with laparoscopic surgery of ovarian endometrioma from Jun 2008 to Jun 2010 were divided into A group and B group.37 cases in A group were unilateral ovarian endometrioma,while 43 cases in B group were bilateral ovarian endometrioma.35 cases with laparoscopic surgery of ovarian teratoma were chose as control group.The change of LH,E2 and FSH before and after operation were compared in each group,and the recovery condition of FSH were followed up by 6 months and 1 year after operation.Results FSH were obviously improved,E2 and LH were obviously decreased in B group after opeation.The difference had statistical significance(P < 0.05).The difference of each hormone level had no statistical significance in A group and control group after operation.Compared with control group,FSH were obviously improved,E2 and LH were obviously decreased in B group after opeation.The difference had statistical significance(P < 0.05).Conclusion Laparoscopic surgery of ovarian endometrioma has certain effect on ovarian reserve function.