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Spontaneous rupture of a hepatic cystadenoma and cystadenocarcinoma: report of two cases
Authors:Lempinen Marko  Halme Leena  Numminen Kirsti  Arola Johanna  Nordin Arno  Mäkisalo Heikki
Affiliation:(1) Clinic of Surgery, Department of Transplantation and Liver Surgery, Helsinki University Hospital, PO Box 263, FIN, 00029 Helsinki, Finland;(2) Clinic of Radiology, Helsinki University Hospital, Helsinki, Finland;(3) Clinic of Pathology, Helsinki University Hospital, Helsinki, Finland
Abstract:Hepatobiliary cystadenomas and cystadenocarcinomas are rare tumors. Differentiating between these tumors and benign hepatic cysts may be difficult. Because of their rarity, diagnosis is often delayed and may result in inaccurate treatment, resulting in unnecessary morbidity and mortality. The purpose of this report is to draw attention to these entities and their complications. We report on two cases with spontaneous rupture of hepatobiliary cystadenoma and cystadenocarcinoma cysts, initially treated as simple hepatic cysts by aspiration, or by aspiration combined with sclerotherapy. The spontaneous rupture of the cysts appeared years after the initial treatment of the cysts, leading in one case to a prolonged stay in an intensive care unit. In both cases, a formal liver resection was carried out and microscopic investigations revealed a mucinous cystadenocarcinoma and cystadenoma. In conclusion, although hepatobiliary cystadenomas and cystadenocarcinomas are rare findings, they should not be forgotten in the diagnostic workshop when examining patients with hepatic cysts. If hepatobiliary cystadenomas and cystadenocarcinomas cannot be excluded following radiological imaging, surgery is recommended.
Keywords:Cystadenoma  Cystadenocarcinoma  Spontaneous rupture  Treatment
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