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脑出血后继发性脑损伤机制
引用本文:程娟,柯开富. 脑出血后继发性脑损伤机制[J]. 国际脑血管病杂志, 2010, 18(10). DOI: 10.3760/cma.j.issn.1673-4165.2010.010.015
作者姓名:程娟  柯开富
作者单位:南通大学附属医院神经内科,226001;南通大学附属医院神经内科,226001
摘    要:脑出血后继发性脑损伤与脑水肿、炎症反应以及其他损伤因素,如补体系统激活、兴奋性氨基酸毒性、血管活性物质释放和自由基损伤等密切相关.脑出血后继发性脑损伤时的神经元死亡方式主要为坏死和凋亡.

关 键 词:脑出血  脑损伤  凝血酶  脑水肿  受体  补体  炎症  细胞凋亡

Mechanisms of secondary brain injury after intracerebral hemorrhage
CHENG Juan,KE Kai-fu. Mechanisms of secondary brain injury after intracerebral hemorrhage[J]. International Journal of Cerebrovascular Diseases, 2010, 18(10). DOI: 10.3760/cma.j.issn.1673-4165.2010.010.015
Authors:CHENG Juan  KE Kai-fu
Abstract:Secondary brain injury is closely associated with brain edema, inflammation response and other injury factors after intracerebral hemorrhage, such as the complement system activation, excitatory amino acid toxicity, the release of vasoactive substances and free radical damage. The main mode of neuronal death during secondary brain injury after intracerebral hemorrhage are necrosis and apoptosis.
Keywords:Cerebral hemorrhage  Brain injuries  Thrombin  Brain edema  Receptors,complcment  Inflammation  Apoptosis
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