| 萎胃散治疗大鼠慢性萎缩性胃炎实验研究 |
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| 引用本文： | 黄明河,蔡锦莲,董新,张尚斌,何沁,陈福如. 萎胃散治疗大鼠慢性萎缩性胃炎实验研究[J]. 中国中西医结合消化杂志, 2000, 8(4): 199-200 |
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| 作者姓名： | 黄明河 蔡锦莲 董新 张尚斌 何沁 陈福如 |
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| 作者单位： | 1. 广东省深圳市中医院消化内科,深圳 518033
2. 广东省深圳市中医院消化内科,深圳 518033 指导者 |
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| 基金项目： | 广东省中医药管理局科研课题（No.97286)△指导者 |
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| 摘 要： | 目的探讨萎胃散治疗慢性萎缩性胃炎(CAG)的疗效及其机制.方法用主动免疫、乙醇、去氧胆酸钠及热糊灌胃同时进行的综合方法,制成大鼠CAG模型.造模后治疗组以萎胃散大、小剂量治疗60d,观察指标以胃粘模固有腺体萎缩程度为依据.对照组仅予生理盐水灌胃.结果治疗组的CAG病变数量明显减少,病理检查可见腺体恢复正常.治疗组与模型组(不给药治疗)比较有显著性差异(P＜0.05).结论萎胃散的应用可使胃粘膜同有腺体增多,有良好的治疗CAG的作用.
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| 关 键 词： | 胃炎,萎缩性 萎胃散 |
| 修稿时间： | 2000-02-15 |
Experimental Study of Wei-Wei San on Rat Chronic Atrophic Gastritis |
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| Huang Minghe,Cai Jinlian,Dong Xin et al Shenzhen Hospital of Traditional Chinese Medicine,Shenzhen. Experimental Study of Wei-Wei San on Rat Chronic Atrophic Gastritis[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2000, 8(4): 199-200 |
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| Authors: | Huang Minghe Cai Jinlian Dong Xin et al Shenzhen Hospital of Traditional Chinese Medicine Shenzhen |
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| Affiliation: | Huang Minghe,Cai Jinlian,Dong Xin et al Shenzhen Hospital of Traditional Chinese Medicine,Shenzhen 518033 |
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| Abstract: | Objective:To explore the effect and the mechanism of Wei Wei San on chronic atrophic gastritis (CAG).Methods:Infusing initiative immunity,alcohol,deoxysodium cholate and heat paste into stomach at the same time for doing CAG model.Control group was infused with normal saline into stomach after model finished.Treatment groups were used high of low dosage Wei Wei San for 60 days,respectively.The observation index included atrophic degree of gastromucosal gland body.Results:The CAG amount of treatment group was reduced obviously.The gastromucosal gland recovered normal state.Compared with the control group,the difference was significant(P< 0 05 ).Conclusion:Wei Wei San can increase the gastric gland amount.So it has the function of treating CAG. |
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| Keywords: | chronic atrophic gastritis Wei Wei San |
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