H型高血压与急性冠脉综合征发病率的关系

目的:探讨H型高血压与急性冠脉综合征发病率的关系。方法:从2011年2月～至2011年11月在湖南师范大学第一附属医院心内科住院的符合入选标准的原发性高血压患者中随机抽取171例,其中以急性冠脉综合征(ACS)入院的82例;没有合并急性冠脉综合征的原发性高血压患者89例。其中按照同型半胱氨酸水平的不同将其分为2组:同型半胱氨酸(Hcy)水平>10μmol/L为H型高血压组(H型组,n=97),Hcy水平≤10μmol/L为单纯高血压组(单纯组,n=74)。比较H型高血压组与单纯高血压组急性冠脉综合征发生率的差异。结果:H型组患者中ACS的发病率(65.853%)大于单纯高血压组ACS的发病率(48.315%)(P<0.05)。ACS组血脂水平与非ACS组血脂水平比较,ACS组血清高密度脂蛋白胆固醇水平低于非ACS患者,P<0.05;而总胆固醇(TCH)水平、甘油三脂(TG)水平、低密度脂蛋白(LDLC)水平无统计学差异。结论:H型高血压与急性冠脉综合征的发生密切相关。

The relationship between the H type hypertension and incidence of acute coronary syndrome

Objective To study the H type hypertension and the relationship with the incidence of acute coronary syndrome.Methods Review analysis of 171 patients in accord with criteria for primary hypertension randomly from Feb.2011 to Nov.2011 in the first affiliated hospital of Hunan Normal University,82 of them with acute coronary syndrome,89 are primary hypertension patients without acute coronary syndrome.In accordance with different level of Serum homocysteine concentration will be divided into 2 groups:H type hypertension group(Hcy>10μmol/L,H group,n= 97),for simple hypertension group(Hcy≤10 μmol/L,simple group n=74).Compare the H type hypertension group’s incidence of the acute coronary syndrome with the simple hypertension group’s.Results The ACS incidence of the H group(65.853%) is higher than that of the simple group(48.315%)(P<0.05).Compare the lipid levels of the ACS group with the not-ACS group,ACS group’s serum high-density lipoprotein(HDL) cholesterol levels is lower than the not-ACS group’s,P<0.05;While the total cholesterol(TCH) level,glycerin three greases(TG) and low density lipoprotein(LDLC) levels without significant difference.Conclusion There is a close relation between the H type hypertension and the occurrence of acute coronary syndrome.