Aneurysm of the interauricular septum and Klinefelter's syndrome

Atrial septal aneurysms are reported secondary to congenital cardiopathies with an increased gradient between the two atrial chambers or primary, usually associated with an alteration in the connective tissues of the heart. We describe a patient with an atrial septal aneurysm and Klinefelter's syndrome, an association not previously reported, that reinforces the relationship of this aneurysm to a connective tissue abnormality.