Solitary pulmonary metastasis arising thirteen years after liver transplantation for HBV-related hepatocellular carcinoma |
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| Authors: | Viola Chiara Asselah Tarik Samuel Didier Durand François Boudjema Hamza Valla Dominique Marcellin Patrick |
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| Institution: | 1. Service d'Hépatologie, INSERM CRB3, University of Paris Ⅶ, H(o)pital,Beaujon, Clichy 92 110, France
2. Centre Hepatobiliary, UPRES 3541, Formation de recherche Claude Bernard Virus et Transplantation, Universite Paris-Sud, H(o)pital Paul Brousse, Villejuif 94800, France |
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| Abstract: | We described a 59-year-old male patient who underwent liver transplantation in 1989 for hepatocellular carcinoma (HCC) complicating hepatitis B virus (HBV) cirrhosis. In 2001 (12 years after liver transplantation), he developed a lung metastasis of HCC without intrahepatic recurrence and the resection was done. In July 2003, he was symptom free without any recurrence. HCC metastasis can develop even after a very long time of liver transplantation. Many HCCs grow slowly, and the growth rate of recurrent tumors in patients receiving immunosuppressive therapy is significantly greater than that of those who do not receive immunosuppressive therapy. |
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| Keywords: | Hepatitis B virus Liver transplantation Hepatocellular carcinoma Metastasis Immuno-suppression |
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