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原发中枢神经系统恶性淋巴瘤的诊断及治疗
引用本文:项威,赵刚,李彬,杜波. 原发中枢神经系统恶性淋巴瘤的诊断及治疗[J]. 陕西肿瘤医学, 2010, 0(1): 152-154
作者姓名:项威  赵刚  李彬  杜波
作者单位:[1]深圳市人民医院神经外科,广东深圳518019 [2]吉林大学第一临床医院神经外科,吉林长春130011 [3]深圳市妇幼保健院,广东深圳518020
摘    要:目的:探讨原发中枢神经系统恶性淋巴瘤(PCNSL)的临床、影像学表现,治疗方案选择和预后。方法:对24例PCNSL的诊断、治疗过程、预后进行回顾性分析。结果:PCNSL的临床表现以颅内压增高、局灶占位性病变损伤症状为主,肿瘤可单发或多发;肿瘤影像学缺乏特异性,确诊依靠病理学诊断。结论:PCNSL恶性度高,预后不良,手术全切率低;对确诊病例采用个体化的手术方案结合术后放、化疗是治疗本病的关键,可显著延长患者生存时间。

关 键 词:原发中枢神经系统恶性淋巴瘤  诊断  治疗

Diagnosis and treatment of primary central nervous system lymphoma
XIANG Wei,ZHAO Gang,LI Bin,DU Bo. Diagnosis and treatment of primary central nervous system lymphoma[J]. Shaanxi Oncology Medicine, 2010, 0(1): 152-154
Authors:XIANG Wei  ZHAO Gang  LI Bin  DU Bo
Affiliation:1Department of Neurosurgery , Shenzhen People's Hospital, Shenzhen 518020, China ;2 First Hospital of Jilin University, Changchun 131100 ;3Department of Gynecology and Obstetrics, Shenzhen People's Maternity Child Healthcare Hospital Radiography, Shenzhen 518020, China)
Abstract:Objective:To investigate the clinical,imaging findings, treatment options and prognosis of primary central nervous system lymphoma (PCNSL). Methods:To review the diagnosis, treatment, prognosis of 24 cases of PCNSL. Results:PCNSL clinical features were increased intraeranial pressure, focal lesions injury symptoms,tumors can be single or multiple,lack of specific tumor imaging, rely on the pathological diagnosis was confirmed. Conclusion: PCNSL has high degree of vicious, poor prognosis, the low rate of total resection surgery ; Surgery combined with radiotherapy and chemotherapy comprehensive treatment is the key of effective treatment.
Keywords:primary central nervous system lymphoma  diagnosis  treatment
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